The film opens with two teenagers flying from New York to Los Angeles on New Years Eve. Their nightmare begins when their plane hits extreme turbulence mid-flight. The relentless weather attack causes panic and terror amongst the passengers until the plane ultimately crashes in a remote government-testing area. The handful of survivors from the crash, bloody and disoriented, are then insistently pursued in the darkness by unknown predators that, unbeknownst to them, are part of the government's top-secret Mesa Experiment.

In the midst of an Australian summer, we meet three sisters. Nina is widowed with two young children. Anna is an aspiring actress unhappily married to a filmmaker. Christine is a med student who is yet to fully come to terms with her sexuality. When their mother Susan's breast cancer returns, the family is faced with choices and the reality of their last Christmas together. Simple and sincere, Little Sparrows celebrates life and the unconditional love of a mother.